Speakers
Description
The theme of this mini-symposium focuses on the mathematical modeling of protein dynamics in the context of neurodegenerative diseases such as Alzheimer’s, Creutzfeldt–Jakob, and Parkinson’s diseases. The proposed approaches span multiple biological scales, ranging from protein–protein interactions to cellular dynamics (protein–cell interactions), and up to tissue-level phenomena, including the spatial spread of pathology across brain regions and the formation of amyloid plaques.
The mathematical tools discussed may include ordinary and delay differential equations, partial differential equations describing aggregation, fragmentation, diffusion, or advection processes, with various structural features such as size, spatial, or combined size–space dependencies. Data-driven approaches, including image analysis and data augmentation using neural networks, are also within the scope of this mini-symposium.
Contributions from all relevant fields and at all scales are welcome. By bringing together diverse modeling strategies and methodologies, this mini-symposium aims to advance our understanding of the complex mechanisms underlying these often fatal diseases, which continue to pose many open and challenging questions.
