Speakers
Description
Cell migration plays a central role in key physiological and pathological contexts, including embryonic development, immune responses, tissue repair, and tumour invasion. It arises from the coordinated interplay of mechanisms acting across multiple spatial and temporal scales: from subcellular events - cytoskeletal remodelling, nuclear deformation, polarization, intracellular signalling - to cell-cell and cell-matrix interactions, and collective behaviours at tissue or population levels.
The multiscale nature of migration poses challenges for quantitative understanding and predictive modelling. Mathematical models can integrate experimental data, test biological hypotheses, and reveal emergent properties inaccessible to single-scale descriptions. A wide variety of frameworks – discrete, continuum and hybrid - has been developed, each capturing complementary aspects of migratory behaviour and enabling the study of phenomena ranging from intracellular force generation to large-scale pattern formation and collective motion.
This mini-symposium brings together contributions on mathematical modelling for cell migration across subcellular, cellular, and population scales, focusing on different aspects of the biological process. The session will provide an integrated overview of current modelling strategies and foster discussion on how multiscale frameworks can enhance our understanding of cell migration in complex biological systems.
