Speaker
Description
Human sleep and daytime sleepiness are fundamentally governed by the intricate interplay of two physiological processes: homeostatic sleep pressure and the circadian rhythm. Homeostatic sleep pressure represents the progressive accumulation of sleep propensity that builds continuously during periods of wakefulness and systematically dissipates during sleep. On the other side, circadian rhythm is an endogenous, self-sustaining oscillation of approximately 24 hours driven by the biological master clock. This biological pacemaker dictates the optimal timing for sleep and wakefulness and is primarily synchronized, by environmental light exposure.
While an extensive body of empirical literature suggests that robust daytime bright light exposure is positively associated with enhanced nighttime sleep architecture, increased sleep efficiency, and reduced fragmentation, the precise mechanistic pathways driving this correlation remain incompletely understood. In this study, we use a mathematical model to investigate how light exposure influences the interaction between sleep pressure and the circadian rhythm in the regulation of sleep
Bibliography
@article{Songetal2023,
author = {Song, Yun Min and Choi, Su Jung and Park, Se Ho and Lee, Soo Jin and Joo, Eun Yeon and Kim, Jae Kyoung},
title = {A real-time, personalized sleep intervention using mathematical modeling and wearable devices},
journal = {SLEEP},
year = {2023},
volume = {46},
doi = {10.1093/sleep/zsad179}
}
