Speakers
Description
During embryonic development, cells differentiate and self-organise with remarkable robustness to form complex tissue structures. These processes arise from tightly coupled interactions between morphogen transport, biochemical signalling, cellular dynamics, and tissue mechanics. Despite significant progress, how these mechanisms act together to drive developmental patterning and morphogenesis remains an open problem.
This minisymposium will focus on mechanochemical modelling approaches for understanding developmental patterning, which involves the roles of tissue mechanics and geometry, cell shape and polarity, cell movement and rearrangements, and morphogen-mediated signalling. Emphasis will be placed on theoretical and computational frameworks that capture feedbacks between chemical and mechanical cues during pattern formation. The goal of the minisymposium is to bring together researchers developing and applying mechanochemical models to developmental systems, fostering discussion on emerging methods, biological insights, and open problems in the field. Example applications include gastrulation, somitogenesis, invagination, and other developmental processes.
