Speakers
Description
Neural systems depend on both cellular mechanisms and organization to execute functioning in the brain. Understanding these processes requires bridging the gap across cellular and organismal levels. This minisymposium explores mechanisms that contribute to brain physiology and regulation, from the micro to the macro, using novel mathematical modeling approaches. By presenting research investigating developmental, structural, and metabolic impacts, this session aims to describe the biological underpinnings governing brain structure and function. Topics include biomechanical and biochemical mechanisms that drive brain development, axonal and brain microstructure estimates to capture underlying biophysical processes, and how type 2 diabetes can give rise to neurodegeneration and Alzheimer's disease. Theoretical frameworks in conjunction with experimental data, qualitative comparisons to imaging data, and numerical simulations lead to insights that improve our understanding of the brain.
