Speaker
Takashi Hiiragi
(Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW))
Description
Embryo patterning coordinates cell differentiation, tissue growth and morphogenesis. Understanding how precision is achieved despite the inherent developmental variabilities remains a challenge. Using early mammalian embryos as a model system, we aim to understand the design principle of multi-cellular organisms. Our studies show that feedbacks between cell fate, polarity and cell/tissue mechanics underlie the robustness in development. I will discuss our recent works.
