Speaker
Stephanie Portet
(Department of Mathematics, University of Manitoba, Winnipeg, MB, Canada)
Description
Intermediate filaments are key components of the cytoskeleton, playing essential roles in cell mechanics, signaling and migration. Their spatiotemporal organization, which supports these functions, results from the interplay between assembly and disassembly processes, as well as retrograde actin flow and motor protein–driven transport. Investigating the different mechanisms involved in the intracellular transport of intermediate filaments requires a combination of experimental setups and complementary biological and mathematical models. In this talk, several examples illustrating these approaches will be presented.
Author
Stephanie Portet
(Department of Mathematics, University of Manitoba, Winnipeg, MB, Canada)
Co-authors
John C. Dallon
(Brigham Young University, Provo, Utah, USA)
Leticia Arias
(University Claude Bernard Lyon 1, Lyon, France)
Pascale Bomont
(University Claude Bernard Lyon 1, Lyon, France)
Sandrine Etienne-Manneville
(Institut Pasteur, Paris, France)
Youngmin Park
(University of Florida, Gainesville, Florida, USA)
