12–17 Jul 2026
University of Graz
Europe/Vienna timezone

The polyhedral structure of the disguised toric locus

MS50-02
13 Jul 2026, 15:20
20m
11.02 - HS (University of Graz)

11.02 - HS

University of Graz

130
Minisymposium Talk Systems Biology and Biochemical Networks Dynamical Analysis of Biochemical Reaction Networks

Speaker

Diego Rojas La Luz (University of Wisconsin–Madison)

Description

Polynomial dynamical systems arise in many applications (e.g., biochemistry, population dynamics) but are hard to analyze because they can display multistability, oscillations, and chaos. Mass-action systems, and in particular complex-balanced (toric) systems, are remarkably stable: they admit a unique attracting equilibrium and rule out oscillations and chaos. We study the set of rate constants for which a mass-action system is dynamically equivalent to a complex-balanced system, the disguised toric locus, and introduce a flux-based toolkit for its analysis and computation. We prove the disguised toric locus is homeomorphic to a prism over the disguised toric flux locus, a polyhedral cone with rich combinatorial structure. This leads to new theoretical results on the geometry of the disguised toric locus: that is a contractible manifold with boundary. This prism/flux viewpoint also brings practical consequences: an explicit computational strategy that, for the first time, computes the full disguised toric locus for many networks of interest. Based on joint work with Boros, Craciun, Jin, and Henriksson (2510.03621)

Author

Diego Rojas La Luz (University of Wisconsin–Madison)

Co-authors

Balázs Boros (University of Szeged) Gheorghe Craciun (University of Wisconsin-Madison) Jiaxin Jin (University of Louisiana at Lafayette) Oskar Henriksson (Max Planck Institute)

Presentation materials

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