Speaker
Sarah Olson
(Worcester Polytechnic Institute, USA)
Description
Microtubule asters–dynamic microtubules anchored at a centrosome–form the spindle poles during cell division. Utilizing the method of regularized Stokeslets, we prescribe the motion of microtubule asters in a confined geometry and compute the resulting hydrodynamic drag on the aster. Moving beyond classical asymptotic approximations, we characterize the drag on a single aster inside a spherical cell as a function of its positions and microtubule distribution. We then extend this to study drag on several interacting asters, corresponding to cellular aster configurations prior to division.
Author
Sarah Olson
(Worcester Polytechnic Institute, USA)
Co-author
Dana Ferranti
(Worcester Polytechnic Institute)
