12–17 Jul 2026
University of Graz
Europe/Vienna timezone

Development of agent-based modelling of STI’s: Can we use AI methods for improving implementation of partnership dynamics?

MS76-01
14 Jul 2026, 15:00
20m
15.06 - HS (University of Graz)

15.06 - HS

University of Graz

92

Speaker

Mirjam Kretzschmar (University Medical Center Utrecht)

Description

With the recent increase in computing power, agent-based simulations have become progressively more complex. There is a growing tendency to include greater detail of sexual networks, disease progression, and targeted interventions into STI models to answer relevant public health questions. However, increasing model complexity also amplifies data requirements, and often necessitates the integration of data from different sources for model parameterization. One key challenge in STI transmission modeling is the accurate representation of the dynamic partnership network. Formation and separation of partnerships depend on many factors, including demographics (age, sex), partnership history, infection status, and an individual’s perceived risk of acquiring infection. AI models offer a promising avenue to better integrate data analysis with agent-based modelling to link partnership dynamics directly to underlying determinants. In a first step to explore such a hybrid model, we integrated an XGBoost algorithm—trained on behavioural survey data—into a static network model to inform decisions of agents to engage in protective behaviour during an outbreak of a respiratory infection. We find that epidemic trajectories are influenced by underlying network structure as well as the adaptive behaviour of agents. For agent-based models of STI our approach may provide a flexible way to incorporate determinants of partnerships, predicting their formation or separation from behaviour surveys.

Author

Mirjam Kretzschmar (University Medical Center Utrecht)

Co-authors

Alexandra Teslya (University Medical Center Utrecht, The Netherlands) Ganna Rozhnova Jacob Roberts Janneke van de Wijgert Joshua Chevalier (UMC Utrecht)

Presentation materials

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