12–17 Jul 2026
University of Graz
Europe/Vienna timezone

Sensitivity of dynamics in Autocatalytic Reaction Networks of Togashi-Kaneko type

MS80-03
14 Jul 2026, 11:20
20m
11.01 - HS (University of Graz)

11.01 - HS

University of Graz

130
Minisymposium Talk Systems Biology and Biochemical Networks Stochastic Chemical Reaction Networks

Speaker

Lea Popovic (Concordia University)

Description

The Togashi–Kaneko (TK) model is a prototypical example of an auto- catalytic reaction network exhibiting dramatic switching behavior that is a result of the stochastic dynamics at small volumes. I will present a study of the TK model with additional mutations, using a stochastic averaging principle to make use of the multi-scale feature of its dynamics. I will demonstrate a sensitivity of the model to even slight departures from symmetry in the autocatalytic reactions, using a detailed analysis of the stationary distribution of the fast process when the state of the slow process is fixed. This is joint work with Yi Fu, HyeWon Kang, Wasiur Khudabukhsh, Greg Rempala and Ruth Williams.

Author

Lea Popovic (Concordia University)

Co-authors

Grzegorz Rempala (Ohio State) Hye-Won Kang (University of Maryland, Baltimore County) Ruth Williams Wasiur Rahman Khuda Bukhsh (University of Nottingham)

Presentation materials

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