12–17 Jul 2026
University of Graz
Europe/Vienna timezone

A Numerical Method for a Singular Integrodifferential Equation Model of Biosensor Dynamics

MS133-03
16 Jul 2026, 11:20
20m
15.11 - HS (University of Graz)

15.11 - HS

University of Graz

102
Minisymposium Talk Numerical, Computational, and Data-Driven Methods Stochastic and Deterministic Methods in Mathematical Biology: From Theory to Computation

Speaker

Ryan Evans (National Institute of Standards and Technology)

Description

Biological field effect transistors are portable and highly sensitive biosensors that show promise as medical diagnostic instruments. During a typical experiment, chemical reactants from solution diffuse onto a surface to bind with receptors that are confined to the surface. This produces a time series signal that may be used to analyze the reaction of interest. In experimentally relevant parameter regimes, a model for these experiments takes the form of a nonlinear and logarithmically singular integrodifferential equation. A numerical method based on a Nystrom discretization and specialized quadrature will be presented, and it will be demonstrated that this method achieves second-order accuracy. Numerical simulation compares favorably with experiment.

Author

Ryan Evans (National Institute of Standards and Technology)

Presentation materials

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