12–17 Jul 2026
University of Graz
Europe/Vienna timezone

Using reference models to compare multicellular simulation frameworks and tools

MS175-01
15 Jul 2026, 11:10
40m
02.11 - HS (University of Graz)

02.11 - HS

University of Graz

117
Minisymposium Talk Multiscale and Multiphysics Modelling Multicellular Reference Models and Applications - The OpenVT Project

Speakers

Inge Wortel (Radboud University) Lorenzo Veschini (Indiana Uniersity) Roman Vetter (ETH Zurich)

Description

In this round-table discussion, we will examine how much variation can be accepted when the same spatial model is implemented in different software tools, or when similar biological systems are represented using different modelling formalisms. Using examples such as tissue monolayer growth and a basic angiogenesis model, we will discuss where differences arise, how they should be interpreted, and whether full reproducibility is a realistic goal.
A central topic will be the choice of comparison metrics. We will ask whether simple summary measures are sufficient to detect meaningful discrepancies, or whether they can hide important differences in spatial behaviour. We will also discuss what level of agreement is reasonable in practice, both across different modelling approaches and across tools based on the same formalism.
The goal of this session is to stimulate discussion on practical standards for comparing spatial models and to clarify what reproducibility should mean in the context of spatiotemporal simulation.

Authors

Inge Wortel (Radboud University) Lorenzo Veschini (Indiana Uniersity) Roman Vetter (ETH Zurich)

Presentation materials

There are no materials yet.