Speakers
Description
Multicellular simulations have become indispensable in understanding complex biological phenomena, from tissue development to disease progression. However, the diversity in simulation methods, ranging from agent-based models to lattice-free models and stochastic particle simulations, poses challenges in terms of reproducibility, modularity, reusability, and integration within multi-scale simulations. The Open VT (Virtual Tissues) project is an engaged international community of researchers - modelers and software engineers who use and develop open source multicellular modeling frameworks. These frameworks allow virtual experiments (simulations) of cell behaviors within tissues and organs.
This minisymposia is part of a pair which aim to present the variety of multicellular simulations being used by the community, along with the efforts to make these simulations replicable and reproducible.
In this part, we will demonstrate the need for standardization and the importance of sharing and reusing models. Within a 40 minute keynote, we present the Open VT projects work on developing a set of Reference Models for multicellular simulations. We then present two scientific applications of multicellular modelling and simulation which demonstrate the potential uses of the developing standards.
